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Israeli study: high-intensity aerobic exercise can significantly reduce the risk of cancer metastasis

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Xinhua News Agency, Jerusalem, November 22 (Reporter Wang Zhuolun and Zhang Tianlang) A new study from Tel Aviv University in Israel found that high-intensity aerobic exercise increases the glucose consumption of internal organs, thereby reducing the energy supply of tumors and reducing the risk of cancer metastasis 72%. Related papers were published in the American Journal of Cancer Research.

The study combined human monitoring data and animal model experiments. The results of monitoring nearly 3,000 healthy volunteers for about 20 years showed that compared with those who did not participate in physical exercise, people who regularly performed high-intensity aerobic exercise had a 72% lower probability of cancer metastasis. In animal model experiments, the researchers found that the spread of melanoma to the lungs, liver, and lymph nodes was significantly reduced in exercised mice compared with non-exercised control mice. They suggest that this inhibition of cancer metastasis is associated with an exercise-induced increase in the rate of glucose consumption in both humans and animal models.

Kamita Levi, a professor at Tel Aviv University who co-led the study, said the lungs, liver and lymph nodes were high sites of cancer metastasis. When analyzing cells from these organs, the researchers found that the number of glucose receptors in the cells increased during high-intensity aerobic exercise, suggesting that increased glucose intake turned these organs into efficient "energy-consuming machines." ", it's like the muscles consume a lot of glucose during exercise.

This may be because internal organs "compete" with muscles for glucose resources during high-intensity aerobic exercise, the researchers said. If the cancer progresses further, the internal organs are starved for energy due to intense competition for glucose, and there is less energy vital for cancer metastasis. Therefore, when a person does regular high-intensity aerobic exercise, the risk of cancer metastasis is also significantly reduced.

(Editors in charge: Yu Yang, Cui Yue)

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